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Casey Theriot

Lactobacillus gasseri electron microscopy.

Feb 9, 2021

Study: Lactobacillus Manipulates Bile Acids to Create Favorable Gut Environment

These findings further elucidate the complicated relationship between bile acids and gut bacteria and could eventually enable researchers to design lactobacilli with therapeutic properties. 

C. diff

Jan 21, 2021

Study: Inflamed Environment is C. diff Paradise

New CVM-led research shows that the inflammation caused by Clostridioides difficile infection gives the pathogen a two-fold advantage. 

Mouse epthelium

Apr 1, 2020

Drug Used to Treat Liver Disease Also Affects C. diff Life Cycle, Reduces Inflammation in Mice

The findings aid understanding of how the drug UDCA may be used in future treatment of C. diff infections in humans. 

NC State CVM Building

Mar 11, 2020

Study Shows CRISPR Effectiveness Against Colitis Pathogen

The study shows the system can be used to effectively target and eliminate the pathogen that causes the chronic, degenerative disease of the colon. 


Mar 2, 2020

Theriot, Lanzas named University Faculty Scholars

The scholars program recognizes faculty for significant academic achievements and contributions to NC State. 

Man in lab coat standing in research lab

Jul 7, 2019

CVM Researcher Awarded Grant for Innovative Disease Work

Matthew Foley has a singular focus: harnessing the body’s own power to fight off the devastating bacterium Clostridioides difficile. Now he’s getting invaluable help to reach his goal.   Foley, a postdoctoral fellow at the NC State College of Veterinary Medicine, has received a prestigious National Institutes of Health T32 Training Grant to continue his promising research… 

microscopic view of digestive disease

Oct 22, 2018

Grants Awarded to GI Research Projects at the CVM

Three NC State College of Veterinary Medicine researchers were awarded grants for digestive disease pilot studies at this month’s Center for Gastrointestinal Biology and Disease Research Day. 

Rajani Thanissery and Casey Theriot

Jun 27, 2018

Compounds Kill C. diff, Don’t Affect Other Gut Bacteria In Vitro

NC State researchers developed a drug-testing pipeline to help identify compounds that worked against the three stages of Clostridium difficile infection, and found that a compound that holds promise for treating antibiotic-resistant bacteria may also be able to control C. difficile infections by killing the harmful bacteria without affecting other bacteria in the gut. Clostridium difficile, or C. diff, is a bacterium that can… 

C. difficile magnified

Mar 28, 2018

A Moveable Feast: Antibiotics Give C. diff a Nutrient-Rich Environment, No Competition

Antibiotic use creates a “banquet” for Clostridium difficile (C. diff), by altering the native gut bacteria that would normally compete with C. diff for nutrients... 

Antimicrobial resistance development in bacteria — like E. coli, (pictured above), can have devastating effects on human health.

Apr 2, 2017

Fighting Antibiotic-Resistant Bacteria in Food Animals

Responsible drug practices and antimicrobial resistance research is a CVM priority. The CVM includes faculty considered experts on such matters who shape the international conversation on approaches on drug use and antimicrobial resistance...