CVM Researchers Receive AKC Canine Health Foundation Grants

Researchers at the NC State University College of Veterinary Medicine have been awarded four grants totaling $347,893 from the AKC Canine Health Foundation (CHF) as part of the organization’s 2012 funding year.

The AKC CHF-funded NC State CVM research projects are:

Grant 1557: High-Resolution Cytogenetic Analysis of Histiocytic Malignancies and Development of a Targeted Assay to Screen for Expression Level Changes
Dr. Matthew Breen, PhD
Project Goal: The goal of this project is to narrow down the search for genes playing a key role in Histiocytic Malignancies and thus move a step closer to developing targeted therapies for canine patients diagnosed with this devastating cancer.
View Grant 1557

Grant 1572: Targeting Neutrophil Activation to Develop Novel Drugs to Treat Respiratory Tract Inflammation in Dogs
Dr. Samuel L. Jones, DVM, PhD
Project Goal: This research group has developed a new compound called the MANS peptide. The goal of the project is to determine if MANS peptide can be used to treat serious inflammatory diseases of the canine respiratory tract.
View Grant 1572

Grant 1591: Discovery of Genetic Susceptibility Loci in Atopic Dermatitis using a Genome-Wide Association Study in West Highland White Terriers
Dr. Natasha J Olby, VetMB PhD
Project Goal: This research team will conduct a genome-wide association study of Atopic Dermatitis in Westies to identify chromosomal regions associated with the disease. The long-term goal is to develop genetic tests that can be used by breeders to decrease the prevalence of this condition.
View Grant 1591

Grant 1592: Investigation into the Genetics of Scottie Cramp: Sequencing of Associated Chromosomal Regions
Dr. Natasha J Olby, VetMB PhD
Project Goal: Following up on previous research funded by CHF, the goal of this project is to use deep sequencing techniques to identify genetic mutations associated with Scottie Cramp.
View Grant 1592

“The selection of these grants represents great potential in advancing the health of all dogs and their owners,” said CHF Chief Executive Officer and General Counsel Terry Warren. “The Foundation is dedicated to funding sound scientific research and disseminating health information that can prevent, treat and cure canine disease.”

the CHF received 109 grant proposals and approved 21 grants to 14 research institutions and universities.

The mission of the American Kennel Club Canine Health Foundation, Inc. is to advance the health of all dogs and their owners by funding sound scientific research and supporting the dissemination of health information to prevent, treat, and cure canine disease.

Posted Nov. 15, 2011